To date many interventions have focused on the patient's role in improving their own cardiometabolic health
Feeling more or less sleepy than normal
Olanzapine-induced weight gain and decreased insulin sensitivity lead to increased expression of TCF7L2 in the liver and skeletal muscle
4, 5
In the short term (<6 weeks), men’s average weight increased by 3
Regarding potential predictors of olanzapine‐related weight gain, some evidence suggests that patients with larger early weight gain (EWG) (weight gain within
Olanzapine (OLZ) is a second generation antipsychotic that is approved for the treatment of schizophrenia, bipolar disorder type 1 as
"Weight gain affects most patients who start taking these antipsychotic drugs and is a well-established side effect of these interventions," he said in a UT Southwestern news release
In a 2019 meta-analysis of 402 RCTs including data from 53,463 participants with multi-episode schizophrenia, olanzapine remained the antipsychotic most likely to
Olanzapine is linked to clinically significant body weight gain ranging from 0
Keywords: antipsychotic For example, olanzapine and clozapine commonly cause weight gain, whereas aripiprazole rarely causes this problem
Tell your doctor if these side effects bother you or do not go away: feeling sleepy in the day; putting on weight or an increase in your appetite Introduction
Olanzapine, a highly-efficacious atypical antipsychotic, is associated with significant side effects, including weight gain, that may impact patients’ treatment experiences and limit its use,” said René S
Olanzapine appeared to be better than quetiapine on overall PANSS response, while quetiapine was significantly better than olanzapine on the disorientation scale only
With the exception of clozapine, whether short- or long-term anthropometric outcomes are being assessed, olanzapine is invariably listed as causing the most
Although not everyone will gain weight the chances of gaining weight on Zyprexa are high
Objective: To evaluate options for the management of weight gain associated with olanzapine therapy
Side Effects
According to clinical studies, about 22
Rate of weight gain is highest in the first six months after commencing treatment however patients continue to gain weight during the course of treatment
Publication types Case Reports Letter MeSH terms Adult Benzodiazepines If the target oral olanzapine dose is 10 mg/day: Initial dose: 210 mg IM every 2 weeks OR 405 mg IM every 4 weeks for the first 8 weeks; When deciding among the alternative treatments, clinicians should consider the increased potential for weight gain and dyslipidemia in this population compared to adults
They can ease your symptoms and help you avoid a relapse (when your symptoms come back), but they can also cause weight gain
5
You may gain weight or have high cholesterol and triglycerides (types of fat) while taking this medicine, especially if you are a teenager