To use the skin patch: Apply the patch right away after removing it from the protective pouch
5 mg of rivastigmine per 24 hours
3 mg/24 hours daily, Zeyzelf® cannot be used to achieve the 13
5 mg, and 6 mg of rivastigmine base for oral administration
Rivastigmine is used to treat confusion ( dementia) related to Alzheimer's disease and to Parkinson's disease
6 mg/24 hr patch If PO dose is 6-12 mg/day, switch to 9
Exelon and Exelon Patch for treating dementia associated with Alzheimer's disease
0 mg per mL
It is available as capsules (1
Donepezil patches (Adlarity) and rivastigmine patches (Exelon) are FDA-approved to treat Alzheimer’s-related dementia
Inactive ingredients are
Follow all instructions closely
3 mg/24 hours patch if well tolerated and cognitive deterioration or functional decline demonstrated; use caution in patients with body-weight less than 50 kg, if Exelon ® (rivastigmine tartrate) is a reversible cholinesterase inhibitor and is known chemically as (S)-N-Ethyl-N-methyl-3-[1-(dimethylamino)ethyl]-phenyl carbamate hydrogen-(2R,3R)-tartrate
Titrate dose as recommended for transdermal dosing for mild-to-moderate Alzheimer dementia
Maintenance dose: After a minimum of four weeks of treatment and if well tolerated, the dose of the patch can be increased to 9
3 mg/24 hours
3 mg of rivastigmine per 24 hours
3 mg/24 hours
Rivastigmine
Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase
The OPTIMA (OPtimising Transdermal Exelon In Mild‐to‐moderate AD) study demonstrated significantly greater efficacy on ADL with 13
3 mg/24 hours EXELON PATCH arm and at a frequency higher than in the 4
3 mg of rivastigmine per 24 hours
Pharmaceutical form A patient on a total daily oral rivastigmine dose of 3 mg can be switched to Exelon Patch 5
The 5 cm 2 patch released 4
Absorption of any remaining rivastigmine following the 24-h application period was shown to occur very slowly
3 mg/24 hours administered once per day; replace with a new patch every
94: EXELON (rivastigmine tartrate) Capsules equivalent to 1
3 mg/24 hours; Dosage Considerations – Should be Given as Follows: Alzheimer's Dementia
uncontrolled movements, especially of the face, neck, and back
Selected from NATIONAL DRUG DATA FILE (NDDF) data included with permission and copyrighted by First Databank, Inc
6 mg/24 h transdermal patch
6 mg/24h, 9
By inhibiting this enzyme, it prevents the breakdown of the neurotransmitter acetylcholine and increases its levels in the brain