See more In this article, we have report a patient developing severe myopathy and rhabdomyolysis after starting rosuvastatin within the recommended dose and without
The risk of very serious side effects is extremely low
The leading cause of death in rhabdomyolysis is acute renal failure (18)
These could be
Although we were not able to obtain rosuvastatin plasma levels, even without such data, according to a standard semiquantitative causality assessment, rosuvastatin can be
unusual bleeding or bruising
Rhabdomyolysis (pronounced “rab-doe-my-ah-luh-suhs”) is a condition that causes your muscles to break down (disintegrate), which leads to muscle death
Case presentation A
In clinical trials of rosuvastatin, about 3 in 10 000 patients acquired severe myopathy
6 Alternatively, one can approach this case with a ‘causal pie’ model, according to which a The study analyzed reports of Crestor side effects sent to the FDA and compared them to similar reports sent for other Statins
Laboratory studies have demonstrated almost a two-fold increase of serum rosuvastatin levels in Asian patients when compared to Caucasian patients
Nontraumatic causes of rhabdomyolysis include: The use of alcohol or illegal drugs such as Two serious medication errors have been identified as possible major factors that synergistically contributed to the development of rosuvastatin-induced rhabdomyolysis
Common signs and symptoms of rhabdomyolysis are weak muscles, muscle stiffness, muscle pain and a change in your pee color
A 72-year-old female was admitted to our hospital due to acute hepatitis B infection
3 University of New Mexico Health Sciences Center, Albuquerque
Your risk if higher if you take other medications that can raise the levels of rosuvastatin (Crestor) in your body
All reports of rhabdomyolysis in VigiBase® in adults with statins until 31 December 2022 Rosuvastatin (Crestor) Simvastatin (Zocor) Pitavastatin brownish urine, get medical attention right away
, estimated glomerular filtration rate <60 ml/min/1
Rarely, some side effects may continue long-term or cause prolonged side effects, even after the drug is stopped
Meta-analyses and prospective Do not prescribe rosuvastatin 40 mg to people with predisposing factors for rhabdomyolysis, People with predisposing factors for rhabdomyolysis
a There are multiple causes of rhabdomyolysis
Statin-associated rhabdomyolysis was first reported in 1988 in a cardiac transplant recipient taking lovastatin
Before starting to take statins, you should In this case report, the possible multifactorial causes for rhabdomyolysis following concomitant use of rosuvastatin and ticagrelor such as old age, polypharmacy, renal impairment, along with pharmacogenetics will be discussed
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