100 mg twice daily, to be taken 30 minutes before food, cilostazol should be initiated by those experienced in the management of intermittent claudication, patients receiving cilostazol should be assessed for improvement after 3 months; consider discontinuation of treatment if there is no clinically relevant improvement in walking distance
How Cilostazol works
Pharmacology Mechanism of Action
Generic Name Cilostazol DrugBank Accession Number DB01166 Background Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties
Cilostazol is an antiplatelet drug and a vasodilator
This condition causes pain in the legs during walking, and goes away with rest
In our study, more than three-fourths of the patients receiving cilostazol CR 200 mg exhibited symptom improvement (78
unusual bleeding or bruising
Cilostazol can increase blood flow and the amount of oxygen that gets to the muscles
[2] It is available as a generic medication
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Food may reduce the absorption of cilostazol
Findings: In patients with mild dementia who had received donepezil and cilostazol (n = 34; 77
Omeprazole may significantly increase the blood levels of cilostazol
Each tablet, in addition to the active ingredient, contains the following inactive ingredients: corn starch, croscarmellose sodium, magnesium stearate, and silicon dioxide
However cilostazol has been shown to increase heart rate by about 5 to 7 beats per minute, and this may put some patients at increased risk of cardiac events (eg, those with stable coronary Usually, cilostazol is taken twice a day on an empty stomach
Cilostazol is not recommended in patients receiving two or more other antiplatelet or anticoagulant treatments
Cilostazol is the first drug to consistently demonstrate clinical efficacy in many double-blind randomised control trials
Although there is an increase in adverse side effects, they are generally mild and treatable
At the time of approval, the United States Food and Drug Administration required an additional long-term safety study to evaluate the effect
Vasodilators like cilostazol increase the distance you can walk before the pain develops
Goal Combinatorial therapy directed at both vascular and neurodegenerative aspects of dementia may offer a promising strategy for treatment of